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. The RNA World, Third EditionCSHL Press .
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Chapters from the Second Edition

Chapters not available online have been updated in the new third edition.

The Origins of RNA and RNA at the Origin
1 Before RNA and After: Geophysical and Geochemical Constraints on Molecular Evolution
3 The Genomic Tag Hypothesis: What Molecular Fossils Tell Us about the Evolution of tRNA
4 Probing RNA Structure, Function, and History by Comparative Analysis
6 Did the RNA World Exploit an Expanded Genetic Alphabet?
7 Aminoacyl-tRNA Synthetases and Self-acylating Ribozymes
9 Introns and the RNA World
How to Build a Functional RNA
12 The Role of Metal Ions in RNA Biochemistry
13 Building a Catalytic Active Site Using Only RNA
14 Ribonuclease P
15 The RNA Folding Problem
Transition to the RNP World
18 Group I and Group II Ribozymes as RNPs: Clues to the Past and Guides to the Future
21 tRNA Splicing: An RNA World Add-on or an Ancient Reaction?
24 Dynamics of the Genetic Code
Appendices
Appendix 1: Structures of Base Pairs Involving at Least Two Hydrogen Bonds
Appendix 2: Schematic Diagrams of Secondary and Tertiary Structure Elements
Appendix 3: Reactions Catalyzed by RNA and DNA Enzymes

 
 
 

 
   
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